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ccr3 agonist ccl11  (R&D Systems)


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    R&D Systems ccr3 agonist ccl11
    The primers used for RT-qPCR analysis.
    Ccr3 Agonist Ccl11, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 30 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ccr3+agonist+ccl11/Recombinant+Mouse+CCL11%2FEotaxin+Protein/pmc08776494-74-2-6
    Average 94 stars, based on 30 article reviews
    ccr3 agonist ccl11 - by Bioz Stars, 2026-10
    94/100 stars

    Images

    1) Product Images from "Acupuncture Alleviates Menstrual Pain in Rat Model via Suppressing Eotaxin/CCR3 Axis to Weak EOS-MC Activation"

    Article Title: Acupuncture Alleviates Menstrual Pain in Rat Model via Suppressing Eotaxin/CCR3 Axis to Weak EOS-MC Activation

    Journal: Evidence-based Complementary and Alternative Medicine : eCAM

    doi: 10.1155/2022/4571981

    The primers used for RT-qPCR analysis.
    Figure Legend Snippet: The primers used for RT-qPCR analysis.

    Techniques Used:

    TN reduced eotaxin and histamine (HIS) levels and decreased the expression of CC chemokine receptor 3 (CCR3) and histamine H1 receptor (H1R) in CCD rats. The levels of eotaxin (a, b), HIS (c, d), and interleukin-6 (IL-6) (e, f) in uterus and plasma were detected by ELISA. The mRNA expression of CCR3 (g) and H1R (h) in the uterus was analyzed by RT-qPCR. (i–k) Representative blots (i), and protein expression levels of CCR3 (j) and H1R (k) in uterus. All data are expressed as the means ± SEM ( n = 6 rats/group). (b–f, j, k) One-way ANOVA followed by the Bonferroni post hoc test was used. (a, g, h) The Tamhane T2 post hoc test was used. ∗∗ P < 0.01 vs. Blank group; ∗ P < 0.05 vs. Blank group; △△ P < 0.01 vs. Model group; △ P < 0.05 vs. Model group.
    Figure Legend Snippet: TN reduced eotaxin and histamine (HIS) levels and decreased the expression of CC chemokine receptor 3 (CCR3) and histamine H1 receptor (H1R) in CCD rats. The levels of eotaxin (a, b), HIS (c, d), and interleukin-6 (IL-6) (e, f) in uterus and plasma were detected by ELISA. The mRNA expression of CCR3 (g) and H1R (h) in the uterus was analyzed by RT-qPCR. (i–k) Representative blots (i), and protein expression levels of CCR3 (j) and H1R (k) in uterus. All data are expressed as the means ± SEM ( n = 6 rats/group). (b–f, j, k) One-way ANOVA followed by the Bonferroni post hoc test was used. (a, g, h) The Tamhane T2 post hoc test was used. ∗∗ P < 0.01 vs. Blank group; ∗ P < 0.05 vs. Blank group; △△ P < 0.01 vs. Model group; △ P < 0.05 vs. Model group.

    Techniques Used: Expressing, Clinical Proteomics, Enzyme-linked Immunosorbent Assay, Quantitative RT-PCR

    CCR3 agonist blocked the effect of TN against CCD-induced menstrual pain. (a) The representative uterine contraction curves of all groups. The representative images of the rat uterine activities. (i–vi) Model, Model + SB328437, Model + Vehicle1, Model + CCL11 + TN, Model + Vehicle2 + TN, and Model + Vehicle1 + TN. (b) The number of contraction wave. (c) The peak-to-peak value. (d) The degree of contraction. Data were analyzed by the Tamhane T2 post hoc test and expressed as means ± SEM ( n = 6 rats/group). ∗ P < 0.05 vs. Model group; △△ P < 0.01 vs. Model + Vehicle2 + TN; △ P < 0.05 vs. Model + Vehicle2 + TN; ## P < 0.01 vs. Model + Vehicle1 + TN; # P < 0.05 vs. Model + Vehicle1 + TN.
    Figure Legend Snippet: CCR3 agonist blocked the effect of TN against CCD-induced menstrual pain. (a) The representative uterine contraction curves of all groups. The representative images of the rat uterine activities. (i–vi) Model, Model + SB328437, Model + Vehicle1, Model + CCL11 + TN, Model + Vehicle2 + TN, and Model + Vehicle1 + TN. (b) The number of contraction wave. (c) The peak-to-peak value. (d) The degree of contraction. Data were analyzed by the Tamhane T2 post hoc test and expressed as means ± SEM ( n = 6 rats/group). ∗ P < 0.05 vs. Model group; △△ P < 0.01 vs. Model + Vehicle2 + TN; △ P < 0.05 vs. Model + Vehicle2 + TN; ## P < 0.01 vs. Model + Vehicle1 + TN; # P < 0.05 vs. Model + Vehicle1 + TN.

    Techniques Used:

    CCR3 agonist abolished the effect of TN against CCD-induced increased ECP expression and HIS level. (a) The representative photomicrographs of ECP immunohistochemical staining of all groups in the rat uterus. (i–vi) Model, Model + SB328437, Model + Vehicle1, Model + CCL11 + TN, Model + Vehicle2 + TN, and Model + Vehicle1 + TN. (b) Histogram of IOD value of ECP in the uterus of CCD rats in each group. (c) The level of HIS in uterus was detected by ELISA. The regions are photographs at 400x magnification. The arrows indicate a positive expression of ECP. All data are expressed as the means ± SEM ( n = 6 rats/group). (b) The Tamhane T2 post hoc test was used. (c) One-way ANOVA followed by the Bonferroni post hoc test was used. ∗∗ P < 0.01 vs. Model group; △△ P < 0.01 vs. Model + Viecle2 + TN; ## P < 0.01 vs. Model + Viecle1 + TN; # P < 0.05 vs. Model + Viecle1 + TN.
    Figure Legend Snippet: CCR3 agonist abolished the effect of TN against CCD-induced increased ECP expression and HIS level. (a) The representative photomicrographs of ECP immunohistochemical staining of all groups in the rat uterus. (i–vi) Model, Model + SB328437, Model + Vehicle1, Model + CCL11 + TN, Model + Vehicle2 + TN, and Model + Vehicle1 + TN. (b) Histogram of IOD value of ECP in the uterus of CCD rats in each group. (c) The level of HIS in uterus was detected by ELISA. The regions are photographs at 400x magnification. The arrows indicate a positive expression of ECP. All data are expressed as the means ± SEM ( n = 6 rats/group). (b) The Tamhane T2 post hoc test was used. (c) One-way ANOVA followed by the Bonferroni post hoc test was used. ∗∗ P < 0.01 vs. Model group; △△ P < 0.01 vs. Model + Viecle2 + TN; ## P < 0.01 vs. Model + Viecle1 + TN; # P < 0.05 vs. Model + Viecle1 + TN.

    Techniques Used: Expressing, Immunohistochemical staining, Staining, Enzyme-linked Immunosorbent Assay

    Related Articles

    Sterility:

    Article Title: Acupuncture Alleviates Menstrual Pain in Rat Model via Suppressing Eotaxin/CCR3 Axis to Weak EOS-MC Activation
    Article Snippet: The CCR3 receptor antagonist SB328437 (ab120648, Abcam, Cambridge, UK), dissolved in DMSO (Vehicle1), was administered intraperitoneally at a dose of 5 mg/kg 30 min prior to the acupuncture. .. The specific CCR3 agonist CCL11 (420-ME-100/CF, R&D Systems, MN, USA), which was reconstituted at 100 μ g/mL in sterile PBS (Vehicle2), was injected intraperitoneally at a dose of 10 μ g/per animal 30 min before the acupuncture. ..

    Injection:

    Article Title: Acupuncture Alleviates Menstrual Pain in Rat Model via Suppressing Eotaxin/CCR3 Axis to Weak EOS-MC Activation
    Article Snippet: The CCR3 receptor antagonist SB328437 (ab120648, Abcam, Cambridge, UK), dissolved in DMSO (Vehicle1), was administered intraperitoneally at a dose of 5 mg/kg 30 min prior to the acupuncture. .. The specific CCR3 agonist CCL11 (420-ME-100/CF, R&D Systems, MN, USA), which was reconstituted at 100 μ g/mL in sterile PBS (Vehicle2), was injected intraperitoneally at a dose of 10 μ g/per animal 30 min before the acupuncture. ..



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    ccr3 agonist ccl11  (R&D Systems)
    94
    R&D Systems ccr3 agonist ccl11
    The primers used for RT-qPCR analysis.
    Ccr3 Agonist Ccl11, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ccr3+agonist+ccl11/Recombinant+Mouse+CCL11%2FEotaxin+Protein/pmc08776494-74-2-6
    Average 94 stars, based on 1 article reviews
    ccr3 agonist ccl11 - by Bioz Stars, 2026-10
    94/100 stars
    		  Buy from Supplier

    Image Search Results


    The primers used for RT-qPCR analysis.

    Journal: Evidence-based Complementary and Alternative Medicine : eCAM

    Article Title: Acupuncture Alleviates Menstrual Pain in Rat Model via Suppressing Eotaxin/CCR3 Axis to Weak EOS-MC Activation

    doi: 10.1155/2022/4571981

    Figure Lengend Snippet: The primers used for RT-qPCR analysis.

    Article Snippet: The specific CCR3 agonist CCL11 (420-ME-100/CF, R&D Systems, MN, USA), which was reconstituted at 100 μ g/mL in sterile PBS (Vehicle2), was injected intraperitoneally at a dose of 10 μ g/per animal 30 min before the acupuncture.

    Techniques:

    TN reduced eotaxin and histamine (HIS) levels and decreased the expression of CC chemokine receptor 3 (CCR3) and histamine H1 receptor (H1R) in CCD rats. The levels of eotaxin (a, b), HIS (c, d), and interleukin-6 (IL-6) (e, f) in uterus and plasma were detected by ELISA. The mRNA expression of CCR3 (g) and H1R (h) in the uterus was analyzed by RT-qPCR. (i–k) Representative blots (i), and protein expression levels of CCR3 (j) and H1R (k) in uterus. All data are expressed as the means ± SEM ( n = 6 rats/group). (b–f, j, k) One-way ANOVA followed by the Bonferroni post hoc test was used. (a, g, h) The Tamhane T2 post hoc test was used. ∗∗ P < 0.01 vs. Blank group; ∗ P < 0.05 vs. Blank group; △△ P < 0.01 vs. Model group; △ P < 0.05 vs. Model group.

    Journal: Evidence-based Complementary and Alternative Medicine : eCAM

    Article Title: Acupuncture Alleviates Menstrual Pain in Rat Model via Suppressing Eotaxin/CCR3 Axis to Weak EOS-MC Activation

    doi: 10.1155/2022/4571981

    Figure Lengend Snippet: TN reduced eotaxin and histamine (HIS) levels and decreased the expression of CC chemokine receptor 3 (CCR3) and histamine H1 receptor (H1R) in CCD rats. The levels of eotaxin (a, b), HIS (c, d), and interleukin-6 (IL-6) (e, f) in uterus and plasma were detected by ELISA. The mRNA expression of CCR3 (g) and H1R (h) in the uterus was analyzed by RT-qPCR. (i–k) Representative blots (i), and protein expression levels of CCR3 (j) and H1R (k) in uterus. All data are expressed as the means ± SEM ( n = 6 rats/group). (b–f, j, k) One-way ANOVA followed by the Bonferroni post hoc test was used. (a, g, h) The Tamhane T2 post hoc test was used. ∗∗ P < 0.01 vs. Blank group; ∗ P < 0.05 vs. Blank group; △△ P < 0.01 vs. Model group; △ P < 0.05 vs. Model group.

    Article Snippet: The specific CCR3 agonist CCL11 (420-ME-100/CF, R&D Systems, MN, USA), which was reconstituted at 100 μ g/mL in sterile PBS (Vehicle2), was injected intraperitoneally at a dose of 10 μ g/per animal 30 min before the acupuncture.

    Techniques: Expressing, Clinical Proteomics, Enzyme-linked Immunosorbent Assay, Quantitative RT-PCR

    CCR3 agonist blocked the effect of TN against CCD-induced menstrual pain. (a) The representative uterine contraction curves of all groups. The representative images of the rat uterine activities. (i–vi) Model, Model + SB328437, Model + Vehicle1, Model + CCL11 + TN, Model + Vehicle2 + TN, and Model + Vehicle1 + TN. (b) The number of contraction wave. (c) The peak-to-peak value. (d) The degree of contraction. Data were analyzed by the Tamhane T2 post hoc test and expressed as means ± SEM ( n = 6 rats/group). ∗ P < 0.05 vs. Model group; △△ P < 0.01 vs. Model + Vehicle2 + TN; △ P < 0.05 vs. Model + Vehicle2 + TN; ## P < 0.01 vs. Model + Vehicle1 + TN; # P < 0.05 vs. Model + Vehicle1 + TN.

    Journal: Evidence-based Complementary and Alternative Medicine : eCAM

    Article Title: Acupuncture Alleviates Menstrual Pain in Rat Model via Suppressing Eotaxin/CCR3 Axis to Weak EOS-MC Activation

    doi: 10.1155/2022/4571981

    Figure Lengend Snippet: CCR3 agonist blocked the effect of TN against CCD-induced menstrual pain. (a) The representative uterine contraction curves of all groups. The representative images of the rat uterine activities. (i–vi) Model, Model + SB328437, Model + Vehicle1, Model + CCL11 + TN, Model + Vehicle2 + TN, and Model + Vehicle1 + TN. (b) The number of contraction wave. (c) The peak-to-peak value. (d) The degree of contraction. Data were analyzed by the Tamhane T2 post hoc test and expressed as means ± SEM ( n = 6 rats/group). ∗ P < 0.05 vs. Model group; △△ P < 0.01 vs. Model + Vehicle2 + TN; △ P < 0.05 vs. Model + Vehicle2 + TN; ## P < 0.01 vs. Model + Vehicle1 + TN; # P < 0.05 vs. Model + Vehicle1 + TN.

    Article Snippet: The specific CCR3 agonist CCL11 (420-ME-100/CF, R&D Systems, MN, USA), which was reconstituted at 100 μ g/mL in sterile PBS (Vehicle2), was injected intraperitoneally at a dose of 10 μ g/per animal 30 min before the acupuncture.

    Techniques:

    CCR3 agonist abolished the effect of TN against CCD-induced increased ECP expression and HIS level. (a) The representative photomicrographs of ECP immunohistochemical staining of all groups in the rat uterus. (i–vi) Model, Model + SB328437, Model + Vehicle1, Model + CCL11 + TN, Model + Vehicle2 + TN, and Model + Vehicle1 + TN. (b) Histogram of IOD value of ECP in the uterus of CCD rats in each group. (c) The level of HIS in uterus was detected by ELISA. The regions are photographs at 400x magnification. The arrows indicate a positive expression of ECP. All data are expressed as the means ± SEM ( n = 6 rats/group). (b) The Tamhane T2 post hoc test was used. (c) One-way ANOVA followed by the Bonferroni post hoc test was used. ∗∗ P < 0.01 vs. Model group; △△ P < 0.01 vs. Model + Viecle2 + TN; ## P < 0.01 vs. Model + Viecle1 + TN; # P < 0.05 vs. Model + Viecle1 + TN.

    Journal: Evidence-based Complementary and Alternative Medicine : eCAM

    Article Title: Acupuncture Alleviates Menstrual Pain in Rat Model via Suppressing Eotaxin/CCR3 Axis to Weak EOS-MC Activation

    doi: 10.1155/2022/4571981

    Figure Lengend Snippet: CCR3 agonist abolished the effect of TN against CCD-induced increased ECP expression and HIS level. (a) The representative photomicrographs of ECP immunohistochemical staining of all groups in the rat uterus. (i–vi) Model, Model + SB328437, Model + Vehicle1, Model + CCL11 + TN, Model + Vehicle2 + TN, and Model + Vehicle1 + TN. (b) Histogram of IOD value of ECP in the uterus of CCD rats in each group. (c) The level of HIS in uterus was detected by ELISA. The regions are photographs at 400x magnification. The arrows indicate a positive expression of ECP. All data are expressed as the means ± SEM ( n = 6 rats/group). (b) The Tamhane T2 post hoc test was used. (c) One-way ANOVA followed by the Bonferroni post hoc test was used. ∗∗ P < 0.01 vs. Model group; △△ P < 0.01 vs. Model + Viecle2 + TN; ## P < 0.01 vs. Model + Viecle1 + TN; # P < 0.05 vs. Model + Viecle1 + TN.

    Article Snippet: The specific CCR3 agonist CCL11 (420-ME-100/CF, R&D Systems, MN, USA), which was reconstituted at 100 μ g/mL in sterile PBS (Vehicle2), was injected intraperitoneally at a dose of 10 μ g/per animal 30 min before the acupuncture.

    Techniques: Expressing, Immunohistochemical staining, Staining, Enzyme-linked Immunosorbent Assay